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Progression-free survival is accurately predicted in patients treated with chemotherapy for epithelial ovarian cancer by the histoculture drug response assay in a prospective correlative clinical trial at a single institution. Mobilization of bone marrow stem cells with StemEnhance improves muscle regeneration in cardiotoxin-induced muscle injury. J Gastrointest Surg. Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system. In vivo gene transfer between interacting human osteosarcoma cell lines is associated with acquisition of enhanced metastatic potential. Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells. Adv Exp Med Biol. Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis. Nestin expression in hair follicle sheath progenitor cells.


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Hofmann died of a heart attack on 29 April , surrounded by several grandchildren and great-grandchildren. High efficiency genetic modification of hair follicles and growing hair shafts. Inhibition of growth and metastasis of triple-negative breast cancer targeted by Traditional Chinese Medicine Tubeimu in orthotopic mice models.

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High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models. Efficacy of camptothecin analog DXf Exatecan Mesylate on human pancreatic cancer in an orthotopic metastatic model. Bouvet M, Hoffman RM. Methionine Restriction and Life-Span Extension.

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Recent advances on in vivo imaging with fluorescent proteins. Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models. Hair follicle-derived blood vessels vascularize tumors in skin and are inhibited by Doxorubicin. His main contribution was to elucidate the chemical structure of the common nucleus of the Scilla glycosides an active principal of Mediterranean squill. Real-time confocal imaging of trafficking of nestin-expressing multipotent stem cells in mouse whiskers in long-term 3-D histoculture. Arch Surg. Lab Invest. J Gastrointest Surg. High-throughput screening for salmonella avirulent mutants that retain targeting of solid tumors.

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Tissue Eng Part C Methods. The role of the intravascular microenvironment in spontaneous metastasis development. Comparison of cancer-cell seeding, viability and deformation in the lung, muscle and liver, visualized by subcellular real-time imaging in the live mouse.

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J Gastrointest Surg. The challenges posed by cancer heterogeneity. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].

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